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What is the difference between systolic and diastolic heart failure?
Name the 5 major classes of antihypertensive medications.
What are the clinical features of Parkinson's disease?
Explain the difference between active and passive immunity.
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"Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia nigra, leading to motor symptoms including bradykinesia, resting tremor, and rigidity..."
What are the three cardinal motor symptoms of Parkinson's disease?
Bradykinesia, resting tremor, and rigidity
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Acute myocardial infarction (MI) is caused by plaque rupture and thrombus formation in a coronary artery, leading to myocardial ischemia and necrosis. ST-elevation MI (STEMI) is characterized by ST-segment elevation on ECG and typically results from complete occlusion of a coronary artery. Non-ST-elevation MI (NSTEMI) lacks ST elevation but shows troponin elevation, often from partial or temporary occlusion.
Treatment for STEMI focuses on immediate reperfusion via primary percutaneous coronary intervention (PCI) or fibrinolytic therapy if PCI is unavailable within 120 minutes. NSTEMI management includes antiplatelet therapy, anticoagulation, and risk stratification to determine timing of coronary angiography.
Both STEMI and NSTEMI patients receive secondary prevention with aspirin, P2Y12 inhibitors, statins, beta-blockers, and ACE inhibitors or ARBs as appropriate. Complications of MI include arrhythmias, heart failure, cardiogenic shock, mechanical complications (e.g., papillary muscle rupture), and pericarditis.
What is the pathophysiology of acute myocardial infarction?
Plaque rupture and thrombus formation in a coronary artery, leading to myocardial ischemia and necrosis.
What is the difference between STEMI and NSTEMI?
STEMI: ST-segment elevation on ECG, typically from complete coronary artery occlusion.
NSTEMI: No ST elevation but elevated troponin, often from partial or temporary occlusion.
What are the treatment approaches for STEMI?
Immediate reperfusion via primary PCI or fibrinolytic therapy if PCI is unavailable within 120 minutes.
What medications are used for secondary prevention after MI?
Aspirin, P2Y12 inhibitors, statins, beta-blockers, and ACE inhibitors or ARBs as appropriate.
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